Sleep-punching disorder may be linked to Parkinson's

Everyone dreams. But less than 1 percent of adults have a rare condition that causes them to act out their dreams while asleep.

During a vivid dream involving lots of action, people with REM sleep behavior disorder, (RBD) may punch, kick, scream, shout, swear or grab someone while sleeping or they may jump out of bed -- injuring themselves or hurting a bedmate in the process. 

RBD episodes happen during rapid-eye-movement (REM) sleep, a stage of shut-eye when dreaming occurs, or roughly every two hours.

Usually the body is "paralyzed" during REM sleep. But this doesn't happen in people with RBD, so their arms and legs are free to move while dreaming. As a result, if someone with RBD is dreaming of being attacked, they may fight back in their sleep. There's medication to treat RBD symptoms, yet doctors have previously known little about who is affected by the disorder other than it is more common in men and typically strikes people after age 50.

For reasons that are still unclear, REM sleep behavior disorder also seems to increase a person's risk for Parkinson's disease and one type of dementia. Some studies have suggested that more than 50 percent of those with this rare sleep disorder may go on to develop a neurodegenerative disease.

To learn more, a recent study published in the journal Neurology tried to determine the risk factors for RBD and whether they were similar to those for Parkinson's disease or dementia.

They compared the lifestyle habits of 347 people with RBD to the same number of people who didn't have this sleep problem but were similar in age and gender. 

The study identified several potential risk factors for RBD, including having a previous head injury, being a farmer, and working in a job with pesticide exposure. All three of these risks have also been linked with Parkinson's disease.

Researchers also found that people who had fewer years of education increase their chances of RBD.

"Many of the risk factors for RBD are the same as for Parkinson's disease, however, it is ultimately where they differ that can teach us the most," says study author Dr. Ronald Postuma, a neurologist and associate professor at McGill University in Montreal, Canada.

One important difference scientists found was that people who smoke were more likely to develop RBD, but nicotine has been shown to reduce the odds of Parkinson's disease. A second difference is that coffee drinking was not linked with the sleep disorder while other studies have suggested it helps protect against Parkinson's disease.

Postuma suspects that in some people, REM sleep behavior disorder can be an important sign of early Parkinson's disease. In these early stages, he says the disease may affect areas of the brain involved in sleep, smell, and bladder control.

As Parkinson's advances, it affects the motor areas of the brain, producing symptoms such as tremors, rigid muscles, and problems with walking or posture.

Someone who is acting out their dreams at night often first learns they're doing this from their sleep partner. Sleep talking or sleep walking is usually something quite different from RBD, points out Postuma.

A specialist at a sleep clinic can confirm the diagnosis. Postuma also recommends that RBD patients should be followed by a neurologist, who can monitor and treat their symptoms should any Parkinson changes emerge. 

 

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Discuss this post

I dream I have and erection, then my wife wakes me up and tells me to quit acting out.

    Reply#1 - Tue Jul 31, 2012 12:04 PM EDT

    How could she tell?

      #1.1 - Tue Jul 31, 2012 3:40 PM EDT
      Reply

      347 people? That is a study to go by? With so many people who have this, that is not even a good indicator, let alone to say that this study is conclusive.

      When they do a study with 3000 people then it will be a study of the condition. This is how all these ideas of what is and is not in the medical field get started.

      Is the best scientific information the medical community has to offer? A crap shoot would get you the same results.

        Reply#2 - Tue Jul 31, 2012 12:29 PM EDT

        It has been mathematically demonstrated that the degree to which a sample is representitive of a population is function of the total size of the sample, regardless of the size of the population, assuming the sample is not a large fraction of the population (say, less than a tenth). Thus, a sample of 300 is just as representitive of a population of 10,000 people as it is of a population of 300 million.

        As for why the sample size is so small, the reason is practicality. Studies like this, which require long observation of patients (more than a few hours) are limited by the resources of the institute conducting the study, and by the willingness of potential subjects to take part in the study.

        Also, ststisytical analysis explicitly accounts for sample size when detecting significant results.

        Lastly, I can assure that 347 is not a small sample.

        • 3 votes
        #2.1 - Tue Jul 31, 2012 3:43 PM EDT
        Reply

        Actually Steven100 - 347 was the number of treatment participants, and they had an equal number of controls. So about 700 people, MORE than enough to attain statistical significance. Obviously you have not taken any statistics classes, and know little about scientific research. Seems like you just want to poopoo this valuable scientific study.

        My father, for as long as any of us can remember, acted out in his sleep. Normally a quiet, soft spoken man, he would swear like a trouper, punch, kick, roll out of bed, scream, etc. It was horrifying to watch or listen to, and obviously my parents had twin beds.

        He was diagnosed with Parkinsons in his 60s and died at the age of 83 - a horrible, long, punishing, humiliating, and cruel time. We always wondered if the "wiring" in his brain was so messed up that it was related to his sleep issues (he did go to a sleep lab but they were no help), his Parkinsons, and even his arrhthymias. Poor Dad!

        Happy ending - my daughter is now starting grad school for neuroscience - and will be researching Parkinsons disease! :)

        • 4 votes
        Reply#3 - Tue Jul 31, 2012 1:19 PM EDT

        PS. Dad also suffered from depression - another "wiring" ailment, we wondered?

          Reply#4 - Tue Jul 31, 2012 1:20 PM EDT

          I punch, kick, try to "catch" things. I also have the sensation of being punched in the stomach. Is this the same thing as described? I thought it was some kind of startle reflex.

            Reply#5 - Tue Jul 31, 2012 4:20 PM EDT

            A lot of people have this reaction...it is caused by watching the news.

              Reply#6 - Tue Jul 31, 2012 4:50 PM EDT

              What this article is talking about is Lewy Body Disease, my Dad had it. One of the first signs of Lewy Body Disease is violent nightmares, it is very important to get diagnosed before being treated with drugs. Some drugs can speed up the disease. Lewy Body Disease is a form of dementia, it is congenital. You can get tested for it but Doctor's don't recommend it because if the insurance companies know that you have it they can drop you from their insurance. For more information about this disease go to:

                Reply#7 - Tue Jul 31, 2012 9:39 PM EDT

                FYI, one of the positives of the Affordable Healthcare Act ('Obamacare') is that insurance companies can no longer cancel your coverage because you are sick...

                  #7.1 - Wed Aug 15, 2012 2:44 PM EDT
                  Reply
                  Comment author avatarDing Batvia Facebook

                  Is there anything that is NOT somehow smoking related? Oh good grief.

                    Reply#8 - Tue Jul 31, 2012 10:00 PM EDT

                    My wife says I fart a lot in my sleep (and let's face, during the day, too), so does that count?

                    Should I get treatment? My wife clearly thinks so.

                      Reply#9 - Wed Aug 1, 2012 7:39 AM EDT
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